Molecular Diagnostic Methods for Detection and Characterization of Human Noroviruses
Haifeng Chen1, *, Yuan Hu2
Identifiers and Pagination:Year: 2016
Issue: Suppl-1, M5
First Page: 78
Last Page: 89
Publisher Id: TOMICROJ-10-78
Article History:Received Date: 13/7/2015
Revision Received Date: 11/1/2016
Acceptance Date: 12/1/2016
Electronic publication date: 14/04/2016
Collection year: 2016
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Human noroviruses are a group of viral agents that afflict people of all age groups. The viruses are now recognized as the most common causative agent of nonbacterial acute gastroenteritis and foodborne viral illness worldwide. However, they have been considered to play insignificant roles in the disease burden of acute gastroenteritis for the past decades until the recent advent of new and more sensitive molecular diagnostic methods. The availability and application of the molecular diagnostic methods have led to enhanced detection of noroviruses in clinical, food and environmental samples, significantly increasing the recognition of noroviruses as an etiologic agent of epidemic and sporadic acute gastroenteritis. This article aims to summarize recent efforts made for the development of molecular methods for the detection and characterization of human noroviruses.