Rapid Identification and Characterization of Francisella by Molecular Biology and Other Techniques
Xin-He Lai1, 2, *, #, Long-Fei Zhao3, #, Xiao-Ming Chen1, 2, 4, Yi Ren1, 5
Identifiers and Pagination:Year: 2016
Issue: Suppl-1, M4
First Page: 64
Last Page: 77
Publisher Id: TOMICROJ-10-64
Article History:Received Date: 13/7/2015
Revision Received Date: 20/10/2015
Acceptance Date: 22/10/2015
Electronic publication date: 14/04/2016
Collection year: 2016
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
Francisella tularensis is the causative pathogen of tularemia and a Tier 1 bioterror agent on the CDC list. Considering the fact that some subpopulation of the F. tularensis strains is more virulent, more significantly associated with mortality, and therefore poses more threat to humans, rapid identification and characterization of this subpopulation strains is of invaluable importance. This review summarizes the up-to-date developments of assays for mainly detecting and characterizing F. tularensis and a touch of caveats of some of the assays.