Catheter Related Escherichia hermannii Sepsis in a Haemodialysis Patient



Cecilie Utke Rank1, *, Peter Lommer Kristensen1, Dennis Schrøder Hansen2, Lisbet Brandi1
1 Department of Cardiology, Nephrology, and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
2 Department of Clinical Microbiology, Herlev and Gentofte Hospital, University Hospital of Copenhagen, Denmark


Article Metrics

CrossRef Citations:
0
Total Statistics:

Full-Text HTML Views: 683
Abstract HTML Views: 475
PDF Downloads: 142
ePub Downloads: 96
Total Views/Downloads: 1396
Unique Statistics:

Full-Text HTML Views: 421
Abstract HTML Views: 244
PDF Downloads: 95
ePub Downloads: 75
Total Views/Downloads: 835



© Rank et al. ; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Nordsjællands Hospital, Hillerød, Dyrehavevej 29, 3400 Hillerød, Denmark; Tel: +45 26 85 82 97; E-mail: cecilieutkerank@gmail.com


Abstract

Escherichia hermannii is an extremely rare etiological agent of invasive infection, and thus, the bacterium was initially considered non-pathogenic. However, in five previously reported case reports E. hermannii has been implicated as the sole pathogen. Our case report describes blood stream infection with E.hermannii in a haemodialysis patient with persisting symptoms, high fever and inflammatory markers despite appropriate antibiotic treatment until replacement of the dialysis catheter. We suspect biofilm formation to be a crucial pathogenic feature for E. hermannii in the maintenance of an infection, which stresses the necessity of antibiotic treatment along with catheter replacement in bloodstream- and catheter-related infection with E. hermannii.

Keywords: Biofilm, Escherichia hermannii, gram-negative bacterial infections, haemodialysis, tunnelled catheter infection.