Etiology and Epidemiology of Catheter Related Bloodstream Infections in Patients Receiving Home Parenteral Nutrition in a Gastromedical Center at a Tertiary Hospital in Denmark
Xiaohui Chen Nielsen 1, 2, *, Ming Chen 2, Anne-Marie Blok Hellesøe 3, Palle Bekker Jeppesen 4, Jonna Gyldenlykke 4, Michael Tvede 2, Leif Percival Andersen 3
Identifiers and Pagination:Year: 2012
First Page: 98
Last Page: 101
Publisher ID: TOMICROJ-6-98
Article History:Received Date: 3/8/2012
Revision Received Date: 18/9/2012
Acceptance Date: 5/10/2012
Electronic publication date: 30/11/2012
Collection year: 2012
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in patients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Enterobacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.